Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204026 | 0.87 | BTK (0.53) | GAAKMT2AEGFRBTKMAPK13 | |
| SCHEMBL5082541 | 0.79 | KMT2A (0.67) | GAAKMT2ANPC1RAB9AHPGD | |
| SCHEMBL5082960 | 0.77 | NPC1 (0.55) | GAAKMT2ANPC1RAB9AHPGD | |
| SCHEMBL9634503 | 0.76 | TGM2 (0.44) | GAAKMT2AEGFRBTKNPC1 | |
| SCHEMBL59858 | 0.71 | TGM2 (0.55) | GAAKMT2ANPC1RAB9AHPGD | |
| SCHEMBL24112688 | 0.71 | TGM2 (0.45) | GAAKMT2AEGFRNPC1RAB9A | |
| SCHEMBL8765952 | 0.71 | GAA (0.51) | GAAKMT2AEGFRBTKHPGD | |
| SCHEMBL648951 | 0.68 | NPC1 (0.62) | GAAEGFRNPC1RAB9AHPGD | |
| SCHEMBL27965029 | 0.68 | TGM2 (0.41) | GAAKMT2AEGFRBTKNPC1 | |
| SCHEMBL27718637 | 0.68 | MAPK13 (0.59) | KMT2AMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028999-B1 | PROCESS FOR THE PREPARATION OF ANTIOXIDANT AMIDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-03-23 | — | — | EP | disclosed |
| US-4286105-A | AMIDATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-08-25 | — | — | US | disclosed |
| EP-0028999-A1 | Process for the preparation of antioxidant amides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-05-20 | — | — | EP | disclosed |