Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31130672 | 0.77 | SRC (0.39) | RIPK1AOC3LMNAADRA2CKDM4E | |
| SCHEMBL12125569 | 0.74 | RIPK1 (0.42) | RIPK1SLC6A4AOC3SLC6A3LMNA | |
| SCHEMBL22519675 | 0.73 | LMNA (0.46) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL1268813 | 0.73 | LMNA (0.46) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL3648024 | 0.72 | ALDH1A1 (0.46) | SLC6A4AOC3SLC6A2SLC6A3LMNA | |
| SCHEMBL28106402 | 0.71 | LMNA (0.44) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL9633963 | 0.70 | TSHR (0.46) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL6076547 | 0.70 | LMNA (0.43) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL9334567 | 0.69 | AOC3 (0.57) | RIPK1SLC6A4AOC3SLC6A2SLC6A3 | |
| SCHEMBL477440 | 0.69 | AOC3 (0.57) | RIPK1SLC6A4AOC3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175167-A | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0441207-A2 | Heteroaryl alkenes, process for their preparation, intermediates and their use | BASF Aktiengesellschaft (DE) | 1991-08-14 | — | — | EP | disclosed |