Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3094174 | 0.84 | NR1H2 (0.36) | ALDH1A1TSHRNR1H2NR1H3 | |
| SCHEMBL9634722 | 0.76 | TSHR (0.39) | ALDH1A1TSHRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9179552 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRNR1H2NR1H3CYP1A2 | |
| SCHEMBL2558125 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAHPGDNPC1 | |
| SCHEMBL2565196 | 0.74 | TSHR (0.47) | ALDH1A1TSHRLMNAHPGDNPC1 | |
| SCHEMBL31193363 | 0.74 | TSHR (0.47) | ALDH1A1TSHRLMNAHPGDNPC1 | |
| SCHEMBL1798315 | 0.72 | TSHR (0.45) | ALDH1A1TSHRLMNAHPGDNPC1 | |
| SCHEMBL5375946 | 0.72 | TSHR (0.45) | ALDH1A1TSHRLMNAHPGDNPC1 | |
| SCHEMBL11395983 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HPGDNR1H2NR1H3CYP3A4 | |
| SCHEMBL7634333 | 0.71 | LMNA (0.46) | ALDH1A1TSHRLMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263436-A | Polyethylene silicon compounds | RHONE-POULENC INDUSTRIES (FR) | 1981-04-21 | — | — | US | disclosed |
| US-4208342-A | Polyethylene silicon compounds | RHONE-POULENC INDUSTRIES (FR) | 1980-06-17 | — | — | US | disclosed |
| US-4180515-A | Organosilicon compounds with functional groups | RHONE-POULENC INDUSTRIES (FR) | 1979-12-25 | — | — | US | disclosed |
| US-4145508-A | Polysiloxane thermoplastic elastomers | RHONE-POULENC INDUSTRIES (FR) | 1979-03-20 | — | — | US | disclosed |