Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 6/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634778 | 0.72 | NQO2 (0.40) | NQO2MTNR1AMTNR1BCYP1A2CYP2C9 | |
| SCHEMBL9635012 | 0.66 | CYP1A2 (0.46) | NQO2MTNR1AMTNR1BCYP1A2CYP2C9 | |
| SCHEMBL9634711 | 0.66 | NQO2 (0.41) | NQO2MTNR1AMTNR1BCYP1A2CYP2C9 | |
| SCHEMBL7785010 | 0.59 | MTNR1A (1.00) | NQO2MTNR1AMTNR1B | |
| SCHEMBL4440336 | 0.57 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL9633688 | 0.56 | BAZ1A (0.51) | CYP1A2CYP2C9CYP2C19NPY5RL3MBTL1 | |
| SCHEMBL14720795 | 0.56 | CYP1A2 (0.75) | CYP1A2CYP2C9CYP2C19NPY5RL3MBTL1 | |
| SCHEMBL8424252 | 0.56 | CYP1A2 (0.60) | CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL6422179 | 0.55 | CYP1A2 (0.73) | CYP1A2CYP2C9CYP2C19NPY5RL3MBTL1 | |
| SCHEMBL23088434 | 0.55 | CYP1A2 (0.77) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337765-B1 | ACYLSULFONAMIDE DERIVATIVES OF ALPHA-CARBOCYCLYLTOLUIC ACIDS USED AS LEUKOTRIENE ANTAGONISTS | ICI AMERICAS INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5095038-A | Antiinflammatory, antiallergens | ICI AMERICAS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0337765-A2 | Acylsulfonamide derivatives of alpha-carbocyclyltoluic acids used as leukotriene antagonists | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |