Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | BAD | Q92934 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094069 | 0.81 | DAO (0.38) | DAOKDRSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7087792 | 0.74 | CES2 (0.53) | DAOSMN1; SMN2CYP1A2CYP2C19KCNMA1 | |
| SCHEMBL7627953 | 0.69 | TCF4 (0.51) | TCF4CTNNB1NQO2MEN1KMT2A | |
| SCHEMBL7620156 | 0.69 | TCF4 (0.51) | TCF4CTNNB1NQO2MEN1KMT2A | |
| SCHEMBL7620158 | 0.69 | TCF4 (0.51) | TCF4CTNNB1NQO2MEN1KMT2A | |
| SCHEMBL8093355 | 0.69 | CYP1A2 (0.42) | DAOSMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL7625379 | 0.68 | PTGS2 (0.54) | TCF4CTNNB1PTGS2 | |
| SCHEMBL7625386 | 0.68 | PTGS2 (0.54) | TCF4CTNNB1PTGS2 | |
| SCHEMBL28228751 | 0.68 | CES2 (0.41) | TCF4CTNNB1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6643910 | 0.66 | DAO (0.47) | DAOSMN1; SMN2CYP2C19KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082974-A | 3-HALOGENO-2,3-DIPHENYLACRYLALDEHYDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND A PHARMACEUTICAL COMPOSITION FOR TREATING HYPERLIPIDEMI | OTSUKA PHARACEUTICAL FACTORY, INC. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0424541-A1 | 3-HALOGENO-2,3-DIPHENYLACRYLALDEHYDE DERIVATIVE, METHOD OF PRODUCTION THEREOF AND CURING AGENT FOR HYPERLIPIDEMIA | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-05-02 | — | — | EP | disclosed |