SCHEMBL9634797

SCHEMBL9634797

C=CC(Br)c1ccccc1C(Br)C=C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2356269 0.84 GABRA1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL2786296 0.84 ALOX15 (0.38) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL9655198 0.84 IDO1 (0.36) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL6438765 0.84 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL21175616 0.80 CA1 (0.46) ALDH1A1CYP2C19TSHR
SCHEMBL7711095 0.80 LMNA (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL7924283 0.80 ALDH1A1 (0.61) ALDH1A1CYP1A2CYP2C9CYP2C19TSHR
SCHEMBL5436325 0.77 ALDH1A1 (0.46) ALDH1A1
SCHEMBL7770234 0.76 ELANE (0.38)
SCHEMBL10644617 0.76 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4774302-A BROMINE, IODINE CONTAINING AROMATIC CATALYSTS NIPPON MEKTRON LIMITED (JP) 1988-09-27 US claimed
US-5096900-A Antidepressants, anxiolytic agents SYNTHELABO (FR) 1992-03-17 US disclosed
US-5081128-A Antidepressants, anxiolytic agents SYNTHELABO (FR) 1992-01-14 US disclosed