Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263836 | 0.89 | SLC6A9 (0.55) | SLC6A9MEN1KMT2ATSHRTP53 | |
| SCHEMBL4772386 | 0.85 | TP53 (0.51) | MEN1KMT2ATP53LMNAALDH1A1 | |
| SCHEMBL10444904 | 0.82 | SLC6A9 (0.67) | SLC6A9MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL9686512 | 0.81 | SLC6A9 (0.68) | SLC6A9MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL10444947 | 0.81 | ALDH1A1 (0.51) | SLC6A9MEN1KMT2ATSHRTP53 | |
| SCHEMBL9685926 | 0.81 | SLC6A9 (0.68) | SLC6A9MEN1KMT2ATSHRLMNA | |
| SCHEMBL16768160 | 0.81 | GAA (0.51) | MEN1KMT2ATSHRTP53LMNA | |
| SCHEMBL7497251 | 0.80 | MEN1 (0.68) | MEN1KMT2ATSHRLMNARAB9A | |
| SCHEMBL9635804 | 0.79 | LMNA (0.47) | MEN1KMT2ATP53LMNAKDM4E | |
| SCHEMBL9634452 | 0.79 | CYP1A2 (0.47) | SLC6A9MEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| US-5086056-A | Treating allergic diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-04 | — | — | US | disclosed |
| US-5011842-A | Antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-30 | — | — | US | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |