Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.47 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882180 | 0.81 | CES2 (0.50) | CES2CES1IDO1TDO2NPC1 | |
| SCHEMBL7478644 | 0.81 | CES2 (0.50) | CES2CES1IDO1TDO2NPC1 | |
| SCHEMBL3107199 | 0.81 | CES2 (0.47) | CES2CES1IDO1TDO2HDAC1 | |
| SCHEMBL9412496 | 0.81 | HIF1A (0.49) | CES2CES1IDO1TDO2HDAC1 | |
| SCHEMBL1121616 | 0.76 | LMNA (0.49) | CES2CES1NPC1RAB9AHTT | |
| SCHEMBL7471753 | 0.76 | CES2 (0.49) | CES2CES1IDO1TDO2HTT | |
| SCHEMBL375156 | 0.74 | MAPK14 (0.40) | CES2CES1MDM2L3MBTL1 | |
| SCHEMBL682581 | 0.73 | CES2 (0.53) | CES2CES1NPC1RAB9AHTT | |
| SCHEMBL8797718 | 0.73 | MEN1 (0.46) | CES2CES1IDO1TDO2MDM2 | |
| SCHEMBL20608089 | 0.72 | NPC1 (0.45) | CES2CES1HDAC1MDM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336142-B1 | Iridium organic complex and electroluminescent device using same | IDEMITSU KOSAN CO (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-8106390-B2 | Metal complex compound and organic electroluminescent device using same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-01-31 | — | — | US | disclosed |
| EP-1647554-B1 | IRIDIUMORGANIC COMPLEX AND ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO (JP) | 2011-08-31 | — | — | EP | disclosed |
| EP-2336142-A2 | Iridium organic complex and electroluminescent device using same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-20110017984-A1 | Metal complex compound and organic electroluminescent device using same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-27 | — | — | US | disclosed |
| US-20100155713-A1 | Metal complex compound and organic electroluminescent device using same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7667228-B2 | Metal complex compound and organic electroluminescent device using same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| EP-1647554-A2 | METAL COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2006-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100155713-A1 | Metal complex compound and organic electroluminescent device using same | EMC2, EED, LAGE3 | CES2 3714/4885CES1 4711/4885IDO1 3706/4885 |
| US-20110017984-A1 | Metal complex compound and organic electroluminescent device using same | EMC2, EED, LAGE3 | CES2 3714/4885CES1 4711/4885IDO1 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.