Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510473 | 0.80 | KDM4E (0.36) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL86317 | 0.70 | POLB (0.42) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL13497663 | 0.70 | POLB (0.42) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL9635196 | 0.68 | NOS1 (0.36) | — | |
| SCHEMBL8853760 | 0.67 | ALDH1A1 (0.44) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL9512627 | 0.65 | BCHE (0.32) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL9635267 | 0.64 | MAPT (0.36) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL9636507 | 0.62 | OPRK1 (0.41) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL9636693 | 0.61 | MAPT (0.35) | NPC1MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL19336264 | 0.61 | RYR2 (0.36) | MAPTRAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |