SCHEMBL9635196

SCHEMBL9635196

CS/C1=N/c2ccccc2SCC2CCCCC12

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.36
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9635057 0.78 NOS1 (0.38) NOS1NOS3NOS2
SCHEMBL9636638 0.75 NOS1 (0.38) NOS1NOS3NOS2
SCHEMBL9636562 0.68 KDM4E (0.44)
SCHEMBL9635209 0.68 NPC1 (0.34)
SCHEMBL11131924 0.66 LMNA (0.45) NOS2
SCHEMBL9635267 0.65 MAPT (0.36)
SCHEMBL9636646 0.65 MAPT (0.34)
SCHEMBL9635103 0.64 NOS1 (0.37) NOS1NOS3NOS2
SCHEMBL7458656 0.63 OPRK1 (0.37)
SCHEMBL9636693 0.63 MAPT (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0368063-B1 PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS BAYER AG (DE) 1992-06-10 EP disclosed
US-4990707-A Process for the ring chlorination of aromatic hydrocarbons BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
EP-0368063-A1 Process for the chlorination in the nucleus of aromatic hydrocarbons BAYER AG (DE) 1990-05-16 EP disclosed