Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636642 | 0.83 | KDM4E (0.56) | KDM4EMAPTKMT2AMEN1TP53 | |
| SCHEMBL9635245 | 0.78 | POLB (0.43) | KDM4EKMT2AMEN1SIGMAR1ALDH1A1 | |
| SCHEMBL9265205 | 0.76 | TACR1 (0.47) | KDM4EMAPTKMT2AMEN1SIGMAR1 | |
| SCHEMBL2921022 | 0.75 | SIGMAR1 (0.58) | KDM4EMAPTKMT2AMEN1TP53 | |
| SCHEMBL2923132 | 0.75 | SIGMAR1 (0.58) | KDM4EMAPTKMT2AMEN1TP53 | |
| SCHEMBL17294949 | 0.74 | SIGMAR1 (0.56) | KDM4EMAPTKMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL3104704 | 0.74 | SIGMAR1 (0.56) | KDM4EMAPTKMT2AMEN1TP53 | |
| SCHEMBL17304776 | 0.74 | SIGMAR1 (0.56) | KDM4EMAPTKMT2AMEN1TP53 | |
| SCHEMBL2917808 | 0.73 | SIGMAR1 (0.52) | KDM4EMAPTKMT2AMEN1TP53 | |
| SCHEMBL1600111 | 0.72 | KMT2A (0.65) | KDM4EKMT2AMEN1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991007405-A1 | SALTS OF 3-AZABICYCLO[3.3.1]NONANES AS ANTIARRHYTHMIC AGENTS, AND PRECURSORS THEREOF | THE BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1991-05-30 | — | — | WO | disclosed |