Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635246 | 0.83 | KDM4E (0.52) | KDM4EMAPTSIGMAR1KMT2ATP53 | |
| SCHEMBL9636794 | 0.77 | CXCR3 (0.43) | KDM4EMAPTSIGMAR1KMT2AMEN1 | |
| SCHEMBL17294949 | 0.77 | SIGMAR1 (0.56) | KDM4EMAPTSIGMAR1KMT2ATP53 | |
| SCHEMBL17304776 | 0.77 | SIGMAR1 (0.56) | KDM4EMAPTSIGMAR1KMT2ATP53 | |
| SCHEMBL9269370 | 0.76 | KMT2A (0.48) | KDM4ESIGMAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2923132 | 0.76 | SIGMAR1 (0.58) | KDM4EMAPTSIGMAR1KMT2ATP53 | |
| SCHEMBL2921022 | 0.76 | SIGMAR1 (0.58) | KDM4EMAPTSIGMAR1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL3104704 | 0.75 | SIGMAR1 (0.56) | KDM4EMAPTSIGMAR1KMT2ATP53 | |
| SCHEMBL1600111 | 0.73 | KMT2A (0.65) | KDM4ESIGMAR1KMT2ATP53MEN1 | |
| SCHEMBL9636641 | 0.73 | TLR9 (0.53) | MAPTTP53MAPK1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |