Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.35 |
| ▸ | ESR1 | P03372 | 12/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635349 | 0.88 | ESR1 (0.43) | ARESR2ESR1ESRRBESRRA | |
| SCHEMBL13748783 | 0.80 | AR (0.42) | ARESR2ESR1CA9TYR | |
| SCHEMBL9636754 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2A | |
| SCHEMBL9635368 | 0.74 | RXRA (0.43) | — | |
| SCHEMBL31365141 | 0.73 | ESR2 (0.39) | ARESR2ESR1CA9MIF | |
| SCHEMBL1979729 | 0.69 | AR (0.42) | ARESR2ESR1CA9MIF | |
| SCHEMBL5332124 | 0.69 | ESR2 (0.42) | ARESR2ESR1CA9TYR | |
| SCHEMBL16953445 | 0.68 | CYP1A2 (0.33) | AR | |
| SCHEMBL18305607 | 0.68 | ALDH1A1 (0.31) | ESR2ESR1MEN1KMT2A | |
| SCHEMBL1697195 | 0.67 | CA9 (0.46) | ARESR2ESR1CA9MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283326-B1 | LIQUID CRYSTAL COMPOUNDS WITH 4-(OPTICALLY ACTIVE ALKYL)-3-CYANOPHENYL GROUPS | Chisso Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-4913838-A | LARGE SPONTANEOUS POLARIZATION VALUE | CHISSO CORPORATION (JP) | 1990-04-03 | — | — | US | disclosed |