Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635323 | 0.88 | AR (0.38) | ESR1ESR2ARESRRBESRRA | |
| SCHEMBL9635368 | 0.83 | RXRA (0.43) | XDHSLC22A12 | |
| SCHEMBL9636754 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AXDH | |
| SCHEMBL13748783 | 0.69 | AR (0.42) | ESR1ESR2ARESRRBESRRA | |
| SCHEMBL11667767 | 0.69 | GABRA1 (0.41) | KMT2AMGLLXDHALOX5 | |
| SCHEMBL21939666 | 0.68 | MCL1 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL5067426 | 0.67 | AR (0.57) | ESR1ESR2ARMMP3 | |
| SCHEMBL2785589 | 0.67 | AR (0.57) | ESR1ESR2ARMMP3MEN1 | |
| SCHEMBL10613827 | 0.67 | AR (0.46) | ESR1ESR2ARMMP3XDH | |
| SCHEMBL9635381 | 0.66 | ESR1 (0.44) | ESR1ESR2ARMMP3ESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283326-B1 | LIQUID CRYSTAL COMPOUNDS WITH 4-(OPTICALLY ACTIVE ALKYL)-3-CYANOPHENYL GROUPS | Chisso Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-4913838-A | LARGE SPONTANEOUS POLARIZATION VALUE | CHISSO CORPORATION (JP) | 1990-04-03 | — | — | US | disclosed |