Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.69 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746735 | 0.92 | MAOA (0.54) | MAOACES1BCHEL3MBTL1TDP1 | |
| Anthrone SCHEMBL28776613 | 0.90 | MAOA (0.78) | MAOACES1BCHEL3MBTL1TDP1 | |
| Anthrone SCHEMBL27554507 | 0.90 | MAOA (0.78) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL5021694 | 0.88 | MAOA (0.82) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL6057371 | 0.86 | MAOA (0.78) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL22361369 | 0.85 | TDP1 (0.62) | MAOACES1BCHEL3MBTL1TDP1 | |
| SCHEMBL27874725 | 0.84 | MAOA (0.58) | MAOACES1BCHEL3MBTL1TDP1 | |
| Benzo[B]Fluorene SCHEMBL30914260 | 0.84 | ALDH1A1 (0.55) | MAOAKDM4EMAPTSMN1; SMN2NPC1 | |
| Benzo[B]Fluorene SCHEMBL599104 | 0.84 | ALDH1A1 (0.55) | MAOAKDM4EMAPTSMN1; SMN2NPC1 | |
| Benzo[B]Fluorene SCHEMBL29367443 | 0.84 | ALDH1A1 (0.55) | MAOAKDM4EMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718622-B2 | Heterocyclic adenosine receptor antagonists | EXELIXIS INC. (US) | 2023-08-08 | — | — | US | claimed |
| US-9416296-B2 | Resist underlayer composition and method for forming pattern using same | DONGJIN SEMICHEM CO., LTD. (KR) | 2016-08-16 | — | — | US | disclosed |
| US-9416296-B2 | Resist underlayer composition and method for forming pattern using same | DONGJIN SEMICHEM CO., LTD. (KR) | 2016-08-16 | — | — | US | disclosed |
| US-9170495-B2 | Phenol monomer, polymer for forming a resist underlayer film including same, and composition for a resist underlayer film including same | DONGJIN SEMICHEM CO., LTD. (KR) | 2015-10-27 | — | — | US | disclosed |
| US-20140319097-A1 | PHENOL MONOMER, POLYMER FOR FORMING A RESIST UNDERLAYER FILM INCLUDING SAME, AND COMPOSITION FOR A RESIST UNDERLAYER FILM INCLUDING SAME | DONGJIN SEMICHEM CO., LTD. (KR) | 2014-10-30 | — | — | US | disclosed |
| WO-2014157881-A1 | RESIST UNDERLAYER COMPOSITION AND METHOD FOR FORMING PATTERN USING SAME | 주식회사 동진쎄미켐 (KR) | 2014-10-02 | — | — | WO | disclosed |
| US-5089374-A | Novel bis-onium salts and the use thereof as photoinitiators | EASTMAN KODAK COMPANY (US) | 1992-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718622-B2 | Heterocyclic adenosine receptor antagonists | ADORA2A, ADORA1, ADORA3 | MAOA 398/4885CES1 953/4885BCHE 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.