SCHEMBL9635797

SCHEMBL9635797

O=c1nc2n(-c3ccccc3)c3ccccc3nc-2c(=O)[nH]1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSR P00390 10/20 0.70
TDP2 O95551 3/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
PRKACA P17612 1/20 0.49
RPS6KB1 P23443 1/20 0.49
GSK3B P49841 1/20 0.49
ROCK1 Q13464 1/20 0.49
RECQL P46063 2/20 0.47
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CRHBP P24387 1/20 0.42
KMT2A Q03164 1/20 0.42
CRHR2 Q13324 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5047468 0.86 GSR (0.60) GSRTDP2MAPK1HTTMEN1
SCHEMBL3476023 0.79 GSR (0.65) GSRTDP2RPS6KB1GSK3BRECQL
SCHEMBL15041038 0.78 RPS6KB1 (0.63) GSRMAPK1HTTPRKACARPS6KB1
SCHEMBL9637273 0.77 ALDH1A1 (0.62) GSRMAPK1HTTMEN1ALDH1A1
SCHEMBL11307165 0.74 GSR (0.55) GSRTDP2MAPK1HTTRECQL
SCHEMBL12287205 0.73 GSR (0.51) GSRHTTRECQLMEN1ALDH1A1
SCHEMBL4747145 0.72 GSR (0.55) GSRTDP2RECQLMEN1KMT2A
SCHEMBL9635970 0.72 HTT (0.54) GSRHTTMEN1ALDH1A1KMT2A
SCHEMBL23918202 0.71 LMNA (0.53) GSRMAPK1HTTMEN1ALDH1A1
SCHEMBL15818173 0.71 RPS6KB1 (0.71) GSRMAPK1HTTPRKACARPS6KB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US claimed
US-5153236-A Comprising an N-aryl-alpha-amino acid and a photosensitizer such as a thixoanthone, isoalloxazine or coumarine; high sensitivity to UV and visible light; storage stability; photoresists; relief images HITACHI CHEMICAL CO., LTD. (JP) 1992-10-06 US disclosed