SCHEMBL9635984

SCHEMBL9635984

CCOc1ccc(-c2cc(C)nc(-c3ccccc3)n2)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.54
GAA P10253 2/20 0.54
CNR1 P21554 2/20 0.54
CNR2 P34972 2/20 0.54
GPR55 Q9Y2T6 2/20 0.54
MAPK10 P53779 1/20 0.54
MAPK1 P28482 3/20 0.46
KMT2A Q03164 4/20 0.45
HPGD P15428 4/20 0.45
MEN1 O00255 3/20 0.45
MAPT P10636 3/20 0.45
ATM Q13315 2/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
TP53 P04637 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634541 0.92 LMNA (0.58) LMNAGAACNR1CNR2GPR55
SCHEMBL9634226 0.90 LMNA (0.56) LMNAGAACNR1CNR2GPR55
SCHEMBL9635558 0.86 LMNA (0.53) LMNAGAACNR1CNR2GPR55
SCHEMBL1468002 0.85 LMNA (0.60) LMNAGAACNR1CNR2GPR55
SCHEMBL29375339 0.85 LMNA (0.60) LMNAGAACNR1CNR2GPR55
SCHEMBL9635991 0.83 ADORA3 (0.50) LMNAGAACNR1CNR2GPR55
SCHEMBL10070443 0.83 LMNA (0.57) LMNAGAACNR1CNR2GPR55
SCHEMBL13506418 0.81 LMNA (0.55) LMNAGAACNR1CNR2GPR55
SCHEMBL9635572 0.80 IDH1 (0.51) LMNAGAAMAPK10KMT2AHPGD
SCHEMBL18839985 0.79 LMNA (0.64) LMNAGAACNR1CNR2GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0280654-B1 PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS CIBA-GEIGY AG (CH) 1992-05-13 EP disclosed
US-4895981-A Using ultraviolet absorber CIBA-GEIGY CORPORATION (US) 1990-01-23 US disclosed