Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629604 | 0.82 | ALDH1A1 (0.37) | LMNAHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10429489 | 0.80 | CASR (0.55) | CASRLMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL14508914 | 0.78 | CASR (0.51) | CASRLMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL9902951 | 0.78 | SNCA (0.41) | LMNAHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28417802 | 0.77 | KMT2A (0.61) | CASRLMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL8848749 | 0.76 | LMNA (0.56) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29362862 | 0.75 | MAPK1 (0.70) | LMNAHTTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL3493614 | 0.75 | MAPK1 (0.70) | LMNAHTTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL9813346 | 0.74 | TIMP3 (0.51) | LMNAHTTSMN1; SMN2ALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL9646716 | 0.73 | MAPK1 (0.68) | LMNAHTTSMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175261-A | Useful for coloring cellulose materials, animal furs or leather | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-29 | — | — | US | disclosed |