Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636210 | 0.84 | ESR1 (0.41) | ESR1ESR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9636221 | 0.76 | CYP4F2 (0.40) | ESR1ESR2MAPTLMNATSHR | |
| SCHEMBL9635109 | 0.76 | PPARG (0.36) | LMNACYP1A2CYP2C19CYP2D6PPARG | |
| SCHEMBL9635130 | 0.75 | TSHR (0.41) | ESR1ESR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL26246442 | 0.69 | SCN1A (0.48) | ESR1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL11609595 | 0.67 | LMNA (0.62) | ESR1ESR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27993246 | 0.67 | TDP1 (0.59) | ESR1ESR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28389614 | 0.66 | LMNA (0.51) | SMN1; SMN2NPC1RAB9ALMNATSHR | |
| SCHEMBL22965811 | 0.65 | CYP4F2 (0.49) | ESR1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL25812489 | 0.65 | ALDH1A1 (0.62) | ESR1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102966-A | Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |