Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636227 | 0.84 | ESR1 (0.40) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL6067577 | 0.83 | ESR1 (0.47) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL10773147 | 0.81 | TDP1 (0.46) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL2978166 | 0.79 | TDP1 (0.61) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL10049486 | 0.78 | TSHR (0.42) | ESR1NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL8385248 | 0.77 | ESR1 (0.59) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL14803622 | 0.77 | KDM4E (0.54) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL13567324 | 0.76 | RAB9A (0.47) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL12376808 | 0.76 | ESR1 (0.41) | ESR1ESR2NPC1RAB9ATDP1 | |
| SCHEMBL6470038 | 0.75 | TDP1 (0.56) | ESR1ESR2NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102966-A | Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |