Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.32 |
| ▸ | F3 | P13726 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635209 | 0.77 | NPC1 (0.34) | KDM4ESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL9635196 | 0.68 | NOS1 (0.36) | — | |
| SCHEMBL8853317 | 0.67 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7655843 | 0.65 | KDM4E (0.43) | KDM4ESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL9510473 | 0.64 | KDM4E (0.36) | KDM4ESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL9635267 | 0.64 | MAPT (0.36) | KDM4ESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL9635214 | 0.63 | BCHE (0.40) | KDM4ESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7504253 | 0.63 | POLB (0.64) | NPC1TDP1POLBKMT2A | |
| SCHEMBL14277889 | 0.63 | POLB (0.64) | NPC1TDP1POLBKMT2A | |
| SCHEMBL7657484 | 0.63 | KDM4E (0.41) | KDM4ESMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |