Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636708 | 0.87 | POLB (0.51) | ALDH1A1POLBGAAPKML3MBTL1 | |
| SCHEMBL17319226 | 0.80 | ALDH1A1 (0.61) | ALDH1A1POLBCYP2C19MAPK1LMNA | |
| SCHEMBL6336383 | 0.79 | CHRNA7 (0.57) | ALDH1A1POLBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8711485 | 0.79 | PAX8 (0.48) | POLBCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9257879 | 0.79 | CHRNB2 (0.46) | ALDH1A1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6319408 | 0.78 | CHRNB2 (0.61) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL9272008 | 0.77 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9264243 | 0.74 | KMT2A (0.46) | ALDH1A1POLBATMSMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL9271468 | 0.73 | KMT2A (0.45) | ALDH1A1POLBATMSMN1; SMN2HPGD | |
| SCHEMBL9636642 | 0.73 | KDM4E (0.56) | ALDH1A1MAPK1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |