Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9636869 | 0.99 | OPRM1 (0.51) | OPRM1OPRK1GPR84HTR1ADRD2 | |
| SCHEMBL9091993 | 0.78 | DRD4 (0.56) | OPRM1OPRK1GPR84HTR1ADRD2 | |
| SCHEMBL27118744 | 0.77 | TACR1 (0.49) | ACHESLC6A4TACR2TACR1 | |
| SCHEMBL8124362 | 0.74 | SLC6A4 (0.56) | HTR1ASLC6A4 | |
| SCHEMBL5242533 | 0.73 | SLC6A4 (0.53) | HTR1ADRD2HTR2AHTTSLC6A4 | |
| SCHEMBL9635358 | 0.72 | — | — | |
| SCHEMBL9091956 | 0.72 | BCHE (0.57) | HTR1ADRD2HTR2AHTT | |
| SCHEMBL5726278 | 0.72 | SLC6A4 (0.47) | GPR84HTR1AMPOSLC6A4TACR2 | |
| SCHEMBL9636831 | 0.71 | GPR84 (0.61) | GPR84HTR1AHTR2AMPOSLC6A4 | |
| SCHEMBL9635354 | 0.71 | GPR84 (0.45) | OPRK1GPR84HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |