Sugi Predict

Sugi Predict / Compounds / SCHEMBL963723

SCHEMBL963723

SCHEMBL963723

CN(C)c1ccc(C(=O)NN)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 6/20 0.61
▸ HDAC6 Q9UBN7 5/20 0.61
▸ ALDH1A1 P00352 5/20 0.59
▸ POLB P06746 1/20 0.59
▸ TDP1 Q9NUW8 1/20 0.59
▸ MAPT P10636 3/20 0.59
▸ HPGD P15428 3/20 0.59
▸ MPO P05164 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ KDM5A P29375 1/20 0.57
▸ BLM P54132 1/20 0.57
▸ GFER P55789 1/20 0.57
▸ PMP22 Q01453 1/20 0.57
▸ HIF1A Q16665 1/20 0.57
▸ HDAC8 Q9BY41 3/20 0.56
▸ KDM4E B2RXH2 2/20 0.56
▸ HDAC3 O15379 2/20 0.56
▸ HDAC2 Q92769 2/20 0.56
▸ HTT P42858 2/20 0.56
▸ OGG1 O15527 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28440165 0.83 CYP2A6 (0.54) HDAC1HDAC6ALDH1A1POLBTDP1
SCHEMBL2678949 0.82 MPO (0.80) HDAC6ALDH1A1POLBTDP1MAPT
SCHEMBL343630 0.82 MPO (0.80) HDAC6ALDH1A1POLBTDP1MAPT
SCHEMBL22015906 0.82 HDAC1 (0.71) HDAC1HDAC6ALDH1A1POLBTDP1
SCHEMBL6674162 0.81 HDAC6 (0.89) HDAC1HDAC6ALDH1A1POLBTDP1
SCHEMBL2567664 0.81 GAA (0.66) HDAC1HDAC6ALDH1A1POLBTDP1
SCHEMBL15328083 0.80 HDAC6 (0.58) HDAC1HDAC6ALDH1A1POLBTDP1
SCHEMBL961379 0.80 MAPT (0.59) HDAC6ALDH1A1POLBMAPTHPGD
SCHEMBL13753321 0.80 ALDH1A1 (0.61) HDAC1HDAC6ALDH1A1POLBTDP1
SCHEMBL28188923 0.79 MPO (0.76) HDAC6ALDH1A1POLBTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 — — CN claimed
CN-118724902-A Preparation method and application of benzoyl hydrazine perylene diimide electron transport layer 南昌航空大学 2024-10-01 — — CN claimed
CN-115433142-A 1,3,4-oxadiazole derivative and preparation method and application thereof 吉林大学 2022-12-06 — — CN claimed
CN-111689973-A Dibenzocaprolactam pyrazolidine compound, preparation method and application 朱翠萍 2020-09-22 — — CN claimed
WO-2007047394-A2 THIOTRIAZOLYL DERIVATIVES EPIX DELAWARE, INC. (US) 2007-04-26 — — WO claimed
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-05 — — US claimed
WO-2002102301-A2 SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-12-27 — — WO claimed
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2002-09-12 — — US claimed
JP-9263522-A — — None — — JP disclosed
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 — — CN disclosed
CN-118724902-A Preparation method and application of benzoyl hydrazine perylene diimide electron transport layer 南昌航空大学 2024-10-01 — — CN disclosed
CN-114466850-B [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine 拜耳股份有限公司 2024-09-10 — — CN disclosed
CN-116730941-B 5-Phenyl-1, 3, 4-oxadiazole compound and preparation method and application thereof 广东省科学院微生物研究所(广东省微生物分析检测中心) 2024-07-02 — — CN disclosed
CN-117915903-A Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof 佛罗里达大学研究基金会公司 2024-04-19 — — CN disclosed
US-4256887-A ANTIGOUT, HYPOURICOMIA MERCK & CO., INC. (US) 1981-03-17 — — US disclosed
US-4198513-A ANTI-GOUT AND ANTI-HYPERURICEMIC AGENTS MERCK & CO., INC. (US) 1980-04-15 — — US disclosed
US-4156085-A ANTIGOUT, XANTHINE OXIDASE INHIBITORS MERCK & CO., INC. (US) 1979-05-22 — — US disclosed
US-4102889-A ANTIGOUT AND ANTIHYPERURICEMIC AGENTS MERCK & CO., INC. (US) 1978-07-25 — — US disclosed
US-4071518-A Di-and tri-substituted 1,2,4-triazoles MERCK & CO., INC. (US) 1978-01-31 — — US disclosed
US-4011218-A ANTI-GOUT, ANTI-HYPERURICEMIC MERCK & CO., INC. (US) 1977-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 HDAC1 87/4885HDAC6 171/4885ALDH1A1 144/4885
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 HDAC1 87/4885HDAC6 171/4885ALDH1A1 144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.