Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.39 |
| ▸ | DHODH | Q02127 | 9/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637462 | 0.87 | BRS3 (0.37) | EIF4EBRS3KDM4E | |
| SCHEMBL9638116 | 0.76 | MLKL (0.45) | HPGD | |
| SCHEMBL18132568 | 0.65 | KDM4E (0.59) | PARP1DHODHKDM4E | |
| SCHEMBL828410 | 0.64 | PARP1 (0.61) | PARP1DHODHKDM4EHPGD | |
| SCHEMBL9197081 | 0.63 | PARP1 (0.38) | PARP1DHODH | |
| SCHEMBL4235564 | 0.63 | CTSA (0.47) | PARP1DHODHKDM4EHPGD | |
| SCHEMBL4734786 | 0.63 | PARP1 (0.60) | PARP1DHODHKDM4EHPGD | |
| SCHEMBL828222 | 0.63 | PARP1 (0.60) | PARP1DHODHKDM4EHPGD | |
| SCHEMBL2789377 | 0.62 | KDM4E (0.60) | PARP1DHODHKDM4EHPGD | |
| SCHEMBL8974533 | 0.62 | CNR1 (0.38) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |