Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.31 |
| ▸ | KDM5A | P29375 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637468 | 0.87 | PARP1 (0.39) | BRS3EIF4EKDM4E | |
| SCHEMBL8868610 | 0.81 | PARP1 (0.36) | BRS3EIF4EEIF4EBP1KDM4E | |
| SCHEMBL9493716 | 0.80 | BRS3 (0.39) | BRS3AGTR1AGTR2 | |
| SCHEMBL9638116 | 0.75 | MLKL (0.45) | APLNR | |
| SCHEMBL9492707 | 0.74 | APLNR (0.34) | APLNRKDM4EMAPTHTT | |
| SCHEMBL9492881 | 0.74 | BRS3 (0.34) | BRS3AGTR1AGTR2 | |
| SCHEMBL9491699 | 0.70 | LMNA (0.35) | APLNRKDM4EMAPTHTT | |
| SCHEMBL9494117 | 0.69 | KDM4E (0.38) | APLNRKDM4EMAPT | |
| SCHEMBL9491571 | 0.68 | KDM4E (0.37) | AGTR1AGTR2APLNRKDM5BKDM5A | |
| SCHEMBL8476711 | 0.67 | KDM4E (0.39) | BRS3KDM4EMAPTHTTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |