SCHEMBL963761

SCHEMBL963761

CCOC(=O)C(CS)[Zn]C(CS)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 1/20 0.42
ALDH1A1 P00352 3/20 0.40
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
CAD P27708 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TRPA1 O75762 1/20 0.34
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
PIN1 Q13526 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL967678 0.83 HCAR2 (0.35) ALDH1A1LMNAHCAR2
SCHEMBL963005 0.79 TSHR (0.39) HSD17B10ALOX15KMT2A
SCHEMBL966812 0.76 TSHR (0.37) LMNAHCAR2
SCHEMBL2875105 0.73 CPB2 (0.60) CPB2ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL7755034 0.73 ALDH1A1 (0.46) CPB2ALDH1A1LMNAHSD17B10ALOX15
SCHEMBL16518684 0.71
SCHEMBL3645078 0.71
SCHEMBL27491433 0.71
SCHEMBL818188 0.71
SCHEMBL964380 0.71 ALDH1A1 (0.43) CPB2ALDH1A1LMNAHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
EP-2280057-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2013-09-11 EP disclosed
EP-2280057-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20110021393-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2011-01-27 US disclosed