Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637649 | 0.78 | L3MBTL1 (0.42) | — | |
| Benzene SCHEMBL7660246 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL11322306 | 0.70 | LMNA (0.40) | — | |
| SCHEMBL11315005 | 0.69 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL23684368 | 0.69 | — | — | |
| SCHEMBL3291349 | 0.69 | — | — | |
| SCHEMBL790 | 0.69 | — | — | |
| SCHEMBL11322303 | 0.68 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL25323764 | 0.67 | — | — | |
| SCHEMBL23708983 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171860-A | Diamino isothiazole-1-oxides and 1,1 dioxides as gastric secretion inhibitors | MERCK & CO., INC. (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0040696-B1 | AMINOTHIADIAZOLES AS GASTRIC SECRETION INHIBITORS | MERCK & CO. INC. (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0067436-B1 | DIAMINO ISOTHIAZOLE -1-OXIDES AND -1,1-DIOXIDES AS GASTRIC SECRETION INHIBITORS | MERCK & CO. INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0067436-A2 | Diamino isothiazole -1-oxides and -1,1-dioxides as gastric secretion inhibitors | MERCK & CO. INC. (US) | 1982-12-22 | — | — | EP | disclosed |