Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637973 | 0.79 | HPN (0.47) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL10696728 | 0.71 | CA1 (0.48) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL9652016 | 0.71 | LMNA (0.36) | MAPT | |
| SCHEMBL10073141 | 0.68 | CYP2C9 (0.47) | MEN1KMT2AMAPTNPC1CYP1A2 | |
| Butane SCHEMBL7456611 | 0.66 | EPHX1 (0.46) | MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9638241 | 0.66 | MMP2 (0.47) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL9638244 | 0.65 | MEN1 (0.33) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL70958 | 0.63 | CA1 (0.55) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL8668939 | 0.63 | CA1 (0.55) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL2853760 | 0.62 | CA1 (0.48) | CA1CA2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153183-A | Antiarthritic agents | TORAY INDUSTRIES, INC. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0440809-A1 | METHYLENEDIPHOSPHONIC ACID COMPOUND AND ANTI-INFLAMMATORY CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 1991-08-14 | — | — | EP | disclosed |