Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746467 | 0.81 | SMN1; SMN2 (0.61) | NISCHHTTHTR1AADRA2ADRD1 | |
| SCHEMBL18100543 | 0.78 | ABCG2 (0.57) | NISCHHTTHTR1AADRA2ADRD1 | |
| SCHEMBL2832695 | 0.78 | ABCG2 (0.57) | NISCHHTTHTR1AADRA2ADRD1 | |
| SCHEMBL18100548 | 0.78 | ABCG2 (0.57) | NISCHHTTHTR1AADRA2ADRD1 | |
| SCHEMBL8002252 | 0.78 | DRD2 (0.40) | NISCHHTTDRD2LTA4H | |
| SCHEMBL447295 | 0.77 | NISCH (0.53) | NISCHHTTHTR1AADRA2ADRD1 | |
| SCHEMBL10532087 | 0.77 | SMN1; SMN2 (0.55) | NISCHHTTHTR1AADRA2ADRD1 | |
| SCHEMBL6013994 | 0.75 | CYP3A4 (0.53) | DRD3DRD2 | |
| SCHEMBL1567701 | 0.74 | NISCH (0.50) | NISCHHTTHTR1AADRA2ADRD1 | |
| SCHEMBL19346227 | 0.74 | CA2 (0.41) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230053726-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | VICKERS-SPLICE CO-INVESTMENT LLC (KY) | 2023-02-23 | — | — | US | disclosed |
| US-20220087917-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2022-03-24 | — | — | US | disclosed |
| US-11077046-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | BIOSPLICE THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-11034682-B2 | Gamma-diketones as wnt/β-catenin signaling pathway activators | SAMUMED, LLC (US) | 2021-06-15 | — | — | US | disclosed |
| US-20200222295-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | MED-PATHWAYS II LIMITED (VG) | 2020-07-16 | — | — | US | disclosed |
| EP-1714677-A1 | Long chain fatty acid dimethylaminopropylamide as levelling agent for dyeing kerationous fibres, or as thickening agent | KAO CORPORATION, S.A. (ES) | 2006-10-25 | — | — | EP | disclosed |
| EP-0169581-B1 | ANTITUSSIVE AND MUCUS REGULATING 2-SUBSTITUTED THIAZOLIDINES | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1989-12-06 | — | — | EP | disclosed |
| US-4857643-A | Antitussive and mucus regulating 2-substituted thiazolidines | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-08-15 | — | — | US | disclosed |
| US-4798898-A | BRONCHODILATORS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-01-17 | — | — | US | disclosed |
| EP-0143570-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONICA CORPORATION (JP) | 1988-01-27 | — | — | EP | disclosed |
| EP-0169581-A2 | Antitussive and mucus regulating 2-substituted thiazolidines | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1986-01-29 | — | — | EP | disclosed |
| US-4548899-A | MAGENTA COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0143570-A2 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1985-06-05 | — | — | EP | disclosed |
| US-4279807-A | FOR POLYVINYL CHLORIDE | M&T CHEMICALS INC. (US) | 1981-07-21 | — | — | US | disclosed |
| US-4036980-A | INSECTICIDES, ACARICIDES | SANDOZ LTD. (CH) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077046-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | GLA, DGKG, DGKA | NISCH 602/4885HTT 2158/4885HTR1A 3349/4885 |
| US-20220087917-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | GLA, DGKG, DGKA | NISCH 602/4885HTT 2158/4885HTR1A 3349/4885 |
| US-20200222295-A1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | GLA, DGKG, DGKA | NISCH 602/4885HTT 2158/4885HTR1A 3349/4885 |
| US-11839679-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | DGKG, DGKA, DNER | NISCH 146/4885HTT 1961/4885HTR1A 3022/4885 |
| US-20230053726-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | GSK3A, GSK3B, WNT1 | NISCH 2459/4885HTT 2107/4885HTR1A 2854/4885 |
| US-11034682-B2 | Gamma-diketones as wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | NISCH 2528/4885HTT 2095/4885HTR1A 2852/4885 |
| US-11673885-B2 | γ-diketones as Wnt/β-catenin signaling pathway activators | GSK3A, GSK3B, WNT1 | NISCH 2451/4885HTT 2026/4885HTR1A 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.