Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516562 | 0.75 | CES2 (0.34) | EPHX1 | |
| SCHEMBL6515565 | 0.73 | CES2 (0.31) | — | |
| SCHEMBL11000103 | 0.71 | CYP1A2 (0.47) | GRM2GRM3EPHX1 | |
| SCHEMBL6521091 | 0.71 | CYP2C19 (0.41) | HPGDLMNAEPHX1 | |
| SCHEMBL6518199 | 0.70 | CES2 (0.31) | — | |
| SCHEMBL6517217 | 0.69 | NAAA (0.38) | LMNAEPHX1 | |
| SCHEMBL4141844 | 0.68 | GRM2 (0.46) | GRM2GRM3HPGDMMP1MMP9 | |
| SCHEMBL25826250 | 0.68 | GRM2 (0.46) | GRM2GRM3HPGDMMP1MMP9 | |
| SCHEMBL28752678 | 0.68 | GRM2 (0.46) | GRM2GRM3HPGDMMP1MMP9 | |
| SCHEMBL7046038 | 0.68 | METAP2 (0.38) | GRM2GRM3KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149754-A | Allyl polymers as antisolilants; halogen-free | ALLIED-SIGNAL INC (US) | 1992-09-22 | — | — | US | disclosed |
| US-5006408-A | Stain-resistant polymers derived from itaconic acid useful as coatings for fibers | ALLIED-SIGNAL INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4925906-A | DURABILITY; NYLONS | ALLIED-SIGNAL INC. (US) | 1990-05-15 | — | — | US | disclosed |