SCHEMBL9638646

SCHEMBL9638646

[NH]c1ccc(S(=O)(=O)O)cc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
HSD17B10 Q99714 4/20 0.42
LMNA P02545 1/20 0.41
CASP6 P55212 2/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 3/20 0.40
NT5E P21589 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA12 O43570 2/20 0.38
CA7 P43166 2/20 0.38
CA14 Q9ULX7 2/20 0.38
CA9 Q16790 2/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL341942 0.83 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNACASP6MAPT
SCHEMBL474108 0.80 APEX1 (0.48) ALDH1A1HSD17B10LMNACASP6MAPT
SCHEMBL29389290 0.80 APEX1 (0.48) ALDH1A1HSD17B10LMNACASP6MAPT
Hydrochloric Acid SCHEMBL9871804 0.78 RAB9A (0.47) ALDH1A1HSD17B10LMNACASP6MAPT
Fluoride SCHEMBL11757109 0.78 APEX1 (0.47) ALDH1A1HSD17B10LMNACASP6MAPT
Hydrochloric Acid SCHEMBL11167399 0.78 RAB9A (0.47) ALDH1A1HSD17B10LMNACASP6MAPT
SCHEMBL126576 0.78 APEX1 (0.47) ALDH1A1HSD17B10LMNACASP6MAPT
SCHEMBL1807429 0.77 ALDH1A1 (0.59) ALDH1A1HSD17B10LMNACASP6MAPT
SCHEMBL3386873 0.77 FLT1 (0.50) ALDH1A1HSD17B10LMNACASP6MAPT
SCHEMBL306418 0.77 ALDH1A1 (0.59) ALDH1A1HSD17B10LMNACASP6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5136028-A Red; colorfastness CIBA-GEIGY CORPORATION (US) 1992-08-04 US disclosed
EP-0428482-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1991-05-22 EP disclosed