Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1248173 | 0.77 | TDP1 (0.44) | GAAMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL14680472 | 0.75 | CYP3A4 (0.44) | ALDH1A1GAAMAPTKMT2AKDM4E | |
| SCHEMBL902711 | 0.72 | NPSR1 (0.44) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL11238708 | 0.70 | POLB (0.31) | POLBL3MBTL1 | |
| SCHEMBL195265 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL12315016 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTSLC2A1 | |
| SCHEMBL1246810 | 0.68 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTKMT2AKDM4E | |
| SCHEMBL916588 | 0.68 | ALDH1A1 (0.55) | ALDH1A1MAPTTDP1SMN1; SMN2RAB9A | |
| SCHEMBL13673475 | 0.67 | LMNA (0.52) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL9551610 | 0.67 | ADRA2A (0.47) | ALDH1A1GAAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395726-B1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS | AlliedSignal Inc. (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0395726-A1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS. | ALLIED SIGNAL INC (US) | 1990-11-07 | — | — | EP | disclosed |
| WO-1989008160-A1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS | ALLIED-SIGNAL INC. (US) | 1989-09-08 | — | — | WO | disclosed |
| US-4839124-A | Reduction of carboxyl end groups in polyester fibers with lactim ethers | ALLIED-SIGNAL INC. (US) | 1989-06-13 | — | — | US | disclosed |