Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HPN | P05981 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15106474 | 0.88 | CYP2C9 (0.55) | MAPTHPNALOX15SIRT5CA2 | |
| SCHEMBL3177529 | 0.79 | ALOX15 (0.71) | MAPTHPNALOX15SIRT5CA2 | |
| SCHEMBL1116345 | 0.79 | ALOX15 (0.71) | MAPTHPNALOX15SIRT5CA2 | |
| SCHEMBL10703508 | 0.79 | MAPT (0.53) | MAPTHPNALOX15SIRT5CA2 | |
| SCHEMBL27878255 | 0.78 | ALDH1A1 (0.53) | MAPTHPNALOX15SIRT5SMN1; SMN2 | |
| Probucol SCHEMBL4150 | 0.77 | HPN (1.00) | MAPTHPNALOX15SIRT5CA2 | |
| SCHEMBL8311264 | 0.77 | MAPT (0.68) | MAPTHPNALOX15SIRT5CA2 | |
| Probucol SCHEMBL5143451 | 0.77 | HPN (1.00) | MAPTHPNALOX15SIRT5CA2 | |
| SCHEMBL9506457 | 0.76 | HPN (0.79) | MAPTHPNALOX15SIRT5CA2 | |
| Probucol SCHEMBL8344652 | 0.76 | ALOX15 (0.95) | MAPTHPNALOX15SIRT5CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104212133-B | A kind of heat-resisting pet resin composition and method of making the same | SUZHOU YUNSHU NEW MATERIAL SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2015-11-04 | — | — | CN | claimed |
| CN-105949603-A | Antioxidative and anti-degradation cable sheath and preparation method thereof | 苏州泰尚新材料有限公司 | 2016-09-21 | — | — | CN | disclosed |
| US-5153183-A | Antiarthritic agents | TORAY INDUSTRIES, INC. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0440809-A1 | METHYLENEDIPHOSPHONIC ACID COMPOUND AND ANTI-INFLAMMATORY CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4613642-A | ANTIOXIDANTS FOR POLYOLEFINS | ETHYL CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |