Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 10/20 | 0.41 |
| ▸ | HMGCR | P04035 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659745 | 0.77 | CA2 (0.49) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9638732 | 0.71 | MAPT (0.63) | HPNMAPTALOX15SIRT5VCAM1 | |
| Probucol SCHEMBL8344272 | 0.71 | HPN (0.81) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL7525968 | 0.70 | HPN (0.52) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9638256 | 0.69 | HPN (0.50) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL27427059 | 0.68 | HPN (0.49) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL78134 | 0.67 | MEN1 (0.61) | MAPTALOX15HMGCRCA2CA1 | |
| SCHEMBL5720628 | 0.67 | MMP2 (0.47) | MAPTCA2LMNAMEN1KMT2A | |
| SCHEMBL27429592 | 0.67 | VCAM1 (0.41) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9637888 | 0.67 | HMGCR (0.44) | HPNMAPTALOX15SIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3077894-A | — | — | None | — | — | JP | disclosed |
| US-5153183-A | Antiarthritic agents | TORAY INDUSTRIES, INC. (JP) | 1992-10-06 | — | — | US | disclosed |
| JP-H0377894-A | METHYLENE DIPHOSPHONIC ACID COMPOUND | TORAY IND INC | 1991-04-03 | — | — | JP | disclosed |