P-Nitrophenol

P-Nitrophenol

SCHEMBL9638804

O=[N+]([O-])c1ccc(O)cc1.c1ccc(COCc2ccccc2)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
AR P10275 1/20 0.54
TSHR P16473 1/20 0.52
IDO1 P14902 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.51
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
AKR1C3 P42330 1/20 0.50
HTT P42858 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
F2RL3 Q96RI0 1/20 0.48
CYP19A1 P11511 1/20 0.48
PPIA P62937 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27712803 0.93 TSHR (0.60) NPC1RAB9AARTSHRIDO1
SCHEMBL19621588 0.91 IDO1 (0.61) NPC1RAB9AARTSHRIDO1
SCHEMBL11441117 0.91 IDO1 (0.61) NPC1RAB9AARTSHRIDO1
SCHEMBL6198529 0.84 IDO1 (0.58) NPC1RAB9ATSHRIDO1CYP1A2
Ether SCHEMBL11441077 0.83 IDO1 (0.53) NPC1RAB9AARTSHRIDO1
P-Nitrophenol SCHEMBL28122623 0.83 ALDH1A1 (0.73) NPC1RAB9ATSHRCRHBPCRHR2
SCHEMBL37463 0.83 IDO1 (0.70) RAB9ATSHRIDO1CYP1A2CYP2C19
P-Nitrophenol SCHEMBL8825058 0.83 ALDH1A1 (0.65) NPC1RAB9ATSHRCRHBPCRHR2
P-Nitrophenol SCHEMBL15203620 0.83 ALDH1A1 (0.64) TSHRCRHBPCRHR2ALDH1A1LMNA
P-Nitrophenol SCHEMBL19019931 0.81 CRHBP (0.53) NPC1RAB9ATSHRCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166403-A Liquid crystals SHOWA DENKO K.K. (JP) 1992-11-24 US disclosed