Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640832 | 0.82 | MAPT (0.49) | SMN1; SMN2HTTTP53NPC1LMNA | |
| SCHEMBL28029397 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2RAB9ATP53NPC1LMNA | |
| SCHEMBL8752498 | 0.77 | TSHR (0.51) | SMN1; SMN2RAB9ATP53NPC1LMNA | |
| SCHEMBL8209654 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2LMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL27744090 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2RAB9ATP53NPC1LMNA | |
| SCHEMBL474709 | 0.75 | KMT2A (0.70) | SMN1; SMN2RAB9ATP53NPC1LMNA | |
| SCHEMBL10390652 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2RAB9ATP53NPC1LMNA | |
| SCHEMBL8752521 | 0.74 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTRAB9ATP53NPC1 | |
| SCHEMBL8215714 | 0.74 | KCNJ5 (0.47) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2328579 | 0.74 | ALDH1A1 (0.59) | SMN1; SMN2RAB9ATP53NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339411-B1 | PROCESS FOR THE PREPARATION OF QUINOXALONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0339411-A1 | Process for the preparation of quinoxalones | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | disclosed |