Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MB | P02144 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639610 | 0.82 | SMN1; SMN2 (0.55) | MAPTALDH1A1TP53KMT2AL3MBTL1 | |
| SCHEMBL8752470 | 0.79 | SMN1; SMN2 (0.47) | MAPTALDH1A1TP53HIF1AKMT2A | |
| SCHEMBL4051682 | 0.78 | ALDH1A1 (0.56) | MAPTALDH1A1TP53HIF1AKMT2A | |
| SCHEMBL7220889 | 0.76 | CA1 (0.47) | MAPTALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL599311 | 0.74 | TDP1 (0.45) | ALDH1A1TP53KMT2AL3MBTL1MEN1 | |
| SCHEMBL3645803 | 0.74 | TDP1 (0.45) | ALDH1A1TP53KMT2AL3MBTL1MEN1 | |
| SCHEMBL15047897 | 0.74 | SMN1; SMN2 (0.57) | MAPTALDH1A1TP53HIF1AKMT2A | |
| SCHEMBL20159187 | 0.74 | ALDH1A1 (0.56) | MAPTALDH1A1TP53HIF1AKMT2A | |
| SCHEMBL11235456 | 0.73 | SMN1; SMN2 (0.55) | MAPTALDH1A1TP53HIF1AKMT2A | |
| SCHEMBL12983946 | 0.72 | SMN1; SMN2 (0.55) | MAPTALDH1A1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339411-B1 | PROCESS FOR THE PREPARATION OF QUINOXALONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0339411-A1 | Process for the preparation of quinoxalones | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | disclosed |