Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638943 | 0.89 | SRD5A2 (0.57) | KMT2ASRD5A2ELANEALDH1A1HPGD | |
| SCHEMBL10620118 | 0.85 | ALDH1A1 (0.41) | LMNASRD5A2CA1CA2ESR1 | |
| SCHEMBL4009058 | 0.83 | ALDH1A1 (0.57) | KMT2ALMNAPOLBALDH1A1CYP2C9 | |
| SCHEMBL480674 | 0.83 | KMT2A (0.54) | KMT2APLA2G10PLA2G2ALMNASRD5A2 | |
| SCHEMBL9357126 | 0.79 | KMT2A (0.54) | KMT2APLA2G10PLA2G2ALMNASRD5A2 | |
| SCHEMBL10348275 | 0.78 | RXRA (0.40) | KMT2ALMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13024171 | 0.78 | PTGS1 (0.49) | KMT2ALMNAESR1ALDH1A1CYP2C9 | |
| SCHEMBL81096 | 0.77 | RARB (0.57) | KMT2AALDH1A1HPGDHSD17B10PLK1 | |
| SCHEMBL10946280 | 0.77 | LMNA (0.59) | KMT2APLA2G10PLA2G2ALMNASRD5A2 | |
| SCHEMBL7532519 | 0.76 | MAPT (0.52) | KMT2ALMNASRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189266-A2 | Purification of haloacetyl derivatives of aromatic hydrocarbons | THE DOW CHEMICAL COMPANY (US) | 1986-07-30 | — | — | EP | claimed |
| US-5098990-A | Reaction of a dialcohol, a diamine or a diacyl aromatic compound with a bis/trichloromethyl ketone | THE DOW CHEMICAL COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4762909-A | Method for making polyketones | THE DOW CHEMICAL COMPANY (US) | 1988-08-09 | — | — | US | disclosed |
| US-4731484-A | Haloacetyl derivatives of aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0215543-A1 | A new process for making polyesters, polyamides and polyketones | THE DOW CHEMICAL COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |