Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.41 |
| ▸ | CA1 | P00915 | 17/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270354 | 0.93 | CA2 (0.45) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL9457858 | 0.93 | CA2 (0.45) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL9489943 | 0.88 | CA1 (0.42) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL8849931 | 0.86 | HSD11B1 (0.43) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL571463 | 0.86 | MMP2 (0.43) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL13893253 | 0.75 | CA1 (0.44) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL777838 | 0.74 | CA2 (0.44) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL9489816 | 0.71 | ALDH1A1 (0.48) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL9457440 | 0.70 | HSD11B1 (0.46) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL1802639 | 0.70 | CA1 (0.46) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500721-A1 | FLUORINATED POLY(ETHER SULFONES) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5084548-A | Films or membranes which are heat resistant | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991007454-A1 | FLUORINATED POLY(ETHER SULFONES) | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-30 | — | — | WO | disclosed |