Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676909 | 0.85 | KMT2A (0.58) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL9641028 | 0.84 | LMNA (0.55) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL8781783 | 0.84 | ELANE (0.60) | KMT2AMEN1LMNAMAPTELANE | |
| SCHEMBL28280156 | 0.82 | KMT2A (0.44) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL15243078 | 0.82 | SMN1; SMN2 (0.57) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL9641430 | 0.81 | ELANE (0.59) | LMNAALDH1A1ELANEHPGDXBP1 | |
| SCHEMBL17864858 | 0.81 | ACR (0.51) | KMT2ALMNAALDH1A1HSD17B10MAPT | |
| SCHEMBL8782055 | 0.80 | FAAH (0.44) | LMNAELANEHPGDESR1HIF1A | |
| SCHEMBL11208401 | 0.79 | RAB9A (0.68) | KMT2AMEN1LMNAALDH1A1RAB9A | |
| SCHEMBL9641949 | 0.79 | ELANE (0.69) | LMNAALDH1A1ELANEHIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292889-B1 | BENZALDEHYDE DERIVATIVES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1992-09-02 | — | — | EP | claimed |
| EP-0292889-A2 | Benzaldehyde derivatives, their preparation and use | BASF Aktiengesellschaft (DE) | 1988-11-30 | — | — | EP | claimed |
| EP-0292889-B1 | BENZALDEHYDE DERIVATIVES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1992-09-02 | — | — | EP | disclosed |
| EP-0292889-A2 | Benzaldehyde derivatives, their preparation and use | BASF Aktiengesellschaft (DE) | 1988-11-30 | — | — | EP | disclosed |