Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283777 | 0.84 | KCNH3 (0.53) | RAB9AALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL3210499 | 0.78 | CHRNA7 (0.51) | RAB9ASMN1; SMN2CHRNB2CHRNA4 | |
| Ethoxycarbonyl Group SCHEMBL28051772 | 0.72 | KDM4E (0.42) | RAB9AALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL3643530 | 0.72 | RAB9A (0.54) | RAB9AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL22851453 | 0.71 | RAB9A (0.53) | RAB9AALDH1A1MEN1KMT2ACHRNB2 | |
| SCHEMBL6047182 | 0.70 | KCNA5 (0.57) | KCNA5KCNH2CHRNB2CHRNA4 | |
| SCHEMBL4507702 | 0.69 | LMNA (0.53) | RAB9AALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL7035415 | 0.69 | MAPT (0.67) | RAB9AALDH1A1HPGDTDP1SMN1; SMN2 | |
| SCHEMBL14376115 | 0.69 | CHRNB2 (0.57) | KCNA5TDP1SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL4383419 | 0.69 | RAB9A (0.50) | RAB9AALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496746-A1 | PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES | THE UPJOHN COMPANY (US) | 1992-08-05 | — | — | EP | disclosed |
| WO-1991006542-A1 | PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | disclosed |