SCHEMBL9642328

SCHEMBL9642328

CC(S)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.46
▸ LMNA P02545 2/20 0.44
▸ TYR P14679 1/20 0.44
▸ GRIA4 P48058 4/20 0.43
▸ NR1H4 Q96RI1 2/20 0.41
▸ TP53 P04637 1/20 0.39
▸ KIF11 P52732 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ GPR35 Q9HC97 1/20 0.38
▸ PDE2A O00408 1/20 0.38
▸ ALDH1A1 P00352 3/20 0.37
▸ AKR1C3 P42330 1/20 0.37
▸ AKR1C2 P52895 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.36
▸ NPC1 O15118 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332099 0.81 ESR1 (0.38) LMNATYR
SCHEMBL548066 0.79 TSHR (0.50) TSHRLMNATYRGRIA4NR1H4
SCHEMBL9621026 0.79 TSHR (0.50) TSHRLMNATYRGRIA4NR1H4
SCHEMBL22899446 0.78 PDE2A (0.55) TSHRKIF11PDE2AALDH1A1AKR1C3
SCHEMBL19772089 0.78 PDE2A (0.55) TSHRKIF11PDE2AALDH1A1AKR1C3
SCHEMBL22223039 0.78 ESR1 (0.52) TSHRALDH1A1HSD17B10HPGDMAPK1
SCHEMBL292572 0.76 TSHR (0.52) TSHRLMNATYRGRIA4NR1H4
SCHEMBL24209319 0.75 PDE2A (0.63) TSHRLMNATYRGRIA4NR1H4
SCHEMBL20804428 0.75 TSHR (0.52) TSHRLMNATYRGRIA4NR1H4
Hydrogen Peroxide SCHEMBL2387288 0.75 CYP2C9 (0.57) TSHRLMNATYRGRIA4NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5162556-A Used for forming a thin metal gold layer or film on a substrate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1992-11-10 — — US claimed
US-20230135117-A1 SOLUTION, SOLUTION STORAGE BODY, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2023-05-04 — — US disclosed
US-20230045851-A1 METHOD FOR PRODUCING RESIST COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2023-02-16 — — US disclosed
US-11573489-B2 Solution, solution storage body, actinic ray-sensitive or radiation-sensitive resin composition, pattern forming method, and manufacturing method of semiconductor device FUJIFILM CORPORATION (JP) 2023-02-07 — — US disclosed
EP-3049085-B1 SGK1 INHIBITORS IN THE TREATMENT OF LONG QT SYNDROME BETH ISRAEL DEACONESS MEDICAL CT INC (US) 2021-06-30 — — EP disclosed
US-10663864-B2 Pattern forming method, method for manufacturing electronic device, and laminate FUJIFILM CORPORATION (JP) 2020-05-26 — — US disclosed
US-20190258168-A1 TREATMENT LIQUID AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2019-08-22 — — US disclosed
EP-2681623-B1 PATTERN FORMING METHOD, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST FILM FUJIFILM CORP (JP) 2019-07-10 — — EP disclosed
US-20190196327-A1 SOLUTION, SOLUTION STORAGE BODY, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2019-06-27 — — US disclosed
US-10248019-B2 Pattern forming method, actinic ray-sensitive or radiation-sensitive resin composition and resist film FUJIFILM CORPORATION (JP) 2019-04-02 — — US disclosed
US-20140272692-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM USING THE SAME, PATTERN FORMING METHOD, MANUFACTURING METHOD OF ELECTRONIC DEVICE, ELECTRONIC DEVICE AND RESIN FUJIFILM CORPORATION (JP) 2014-09-18 — — US disclosed
US-8808965-B2 Pattern forming method, pattern, chemical amplification resist composition and resist film FUJIFILM CORPORATION (JP) 2014-08-19 — — US disclosed
US-20120156618-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-06-21 — — US disclosed
US-20120094237-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2012-04-19 — — US disclosed
US-20120034559-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM THEREFROM AND METHOD OF FORMING PATTERN THEREWITH FUJIFILM CORPORATION (JP) 2012-02-09 — — US disclosed
US-20110159433-A1 PHOTOSENSITIVE COMPOSITION, PATTERN-FORMING METHOD USING THE COMPOSITION, AND RESIN USED IN THE COMPOSITION FUJIFILM CORPORATION (JP) 2011-06-30 — — US disclosed
WO-2010061977-A2 PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2010-06-03 — — WO disclosed
US-20070141513-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-06-21 — — US disclosed
US-20070003871-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-04 — — US disclosed
US-5162556-A Used for forming a thin metal gold layer or film on a substrate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1992-11-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110159433-A1 PHOTOSENSITIVE COMPOSITION, PATTERN-FORMING METHOD USING THE COMPOSITION, AND RESIN USED IN THE COMPOSITION SUN2, LCP1, PHYKPL TSHR 4097/4885LMNA 1348/4885TYR 79/4885
US-10248019-B2 Pattern forming method, actinic ray-sensitive or radiation-sensitive resin composition and resist film ACTR3, RXRA, RARA TSHR 3293/4885LMNA 1393/4885TYR 3703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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