Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644404 | 0.90 | TRPV1 (0.40) | TRPV1ESR1ESR2HPGDHSD17B1 | |
| SCHEMBL9644283 | 0.82 | HPGD (0.46) | TRPV1ESR1ESR2HPGDTTR | |
| SCHEMBL9645576 | 0.79 | KMT2A (0.39) | HPGDKMT2AHSD17B10MRGPRX4 | |
| SCHEMBL9313692 | 0.75 | HSD17B1 (0.36) | TRPV1ESR1ESR2HPGDHSD17B1 | |
| SCHEMBL9644001 | 0.73 | STK39 (0.47) | ESR1ESR2HPGDESRRASTK39 | |
| SCHEMBL9314085 | 0.72 | ESR1 (0.37) | ESR1ESR2HPGDMEN1KMT2A | |
| SCHEMBL10482067 | 0.72 | AR (0.36) | TRPV1AR | |
| SCHEMBL10592756 | 0.72 | TRPV1 (0.42) | TRPV1HPGDHSD17B1HSD17B2TTR | |
| SCHEMBL9644433 | 0.70 | KMT2A (0.37) | HPGDKMT2AHSD17B10 | |
| SCHEMBL9811785 | 0.70 | P2RX7 (0.34) | HPGDMAPTNPSR1POLBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166402-A | Herbicidal α-(5-aryloxy-naphthalen-1-yl-oxy)-propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0508263-A2 | Derivatives of alpha-(5 aryloxy-1 naphthyloxy)-carboxylic acid | BAYER AG (DE) | 1992-10-14 | — | — | EP | disclosed |
| EP-0309864-B1 | ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-PROPIONIC-ACID DERIVATIVES | BAYER AG (DE) | 1991-05-22 | — | — | EP | disclosed |
| US-4994601-A | Postemergence herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-19 | — | — | US | disclosed |