Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 12/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314085 | 0.82 | ESR1 (0.37) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL9644404 | 0.81 | TRPV1 (0.40) | HSD17B1HSD17B2ARESR1ESR2 | |
| SCHEMBL9315737 | 0.78 | KMT2A (0.39) | KMT2AGAASMN1; SMN2APEX1 | |
| SCHEMBL9854839 | 0.78 | LMNA (0.33) | GAASMN1; SMN2NPSR1HPGDKDM4E | |
| SCHEMBL9710663 | 0.77 | AR (0.37) | ARESR1ESR2MEN1KMT2A | |
| SCHEMBL9854932 | 0.77 | F9 (0.43) | GAAMAPTSMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL9643156 | 0.75 | TRPV1 (0.41) | HSD17B1HSD17B2ARESR1ESR2 | |
| SCHEMBL9711013 | 0.72 | AR (0.37) | ARESR1ESR2MEN1KMT2A | |
| SCHEMBL9644283 | 0.72 | HPGD (0.46) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL9313686 | 0.72 | KDM4E (0.41) | ESR1ESR2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300676-A | Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0453842-A2 | Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |