Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643177 | 0.88 | ERN1 (0.44) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL9863360 | 0.84 | TRPA1 (0.43) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL2465452 | 0.81 | TRPA1 (0.41) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL9497243 | 0.81 | ALDH1A1 (0.53) | TRPA1PTGS1CACNA1CALDH1A1GAA | |
| SCHEMBL6537850 | 0.81 | TRPA1 (0.55) | LMNATRPA1PTGS1CACNA1CHTT | |
| SCHEMBL3191477 | 0.77 | GABRA1 (0.41) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL11174900 | 0.75 | ACHE (0.38) | TRPA1PTGS1CACNA1CALDH1A1GAA | |
| SCHEMBL9344182 | 0.72 | ALDH1A1 (0.44) | LMNATRPA1ALDH1A1GAAALOX12 | |
| SCHEMBL339292 | 0.72 | TRPA1 (0.67) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL9061064 | 0.71 | HSP90AA1 (0.41) | TRPA1PTGS1CACNA1CALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288582-B1 | PROCESS FOR PRODUCING ALKYL GROUP-SUBSTITUTED AROMATIC HYDROCARBONS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-02 | — | — | EP | claimed |