Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | USP4 | Q13107 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643781 | 0.96 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TDP1ATMABCB11 | |
| SCHEMBL9641852 | 0.94 | ABCB11 (0.48) | ALDH1A1L3MBTL1TDP1ATMABCB11 | |
| SCHEMBL9641776 | 0.88 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1TDP1ATMABCB11 | |
| SCHEMBL9642749 | 0.87 | ABCB11 (0.53) | ALDH1A1L3MBTL1ABCB11SMN1; SMN2UCHL1 | |
| SCHEMBL9641714 | 0.86 | ABCB11 (0.41) | ALDH1A1L3MBTL1TDP1ATMABCB11 | |
| SCHEMBL9641750 | 0.84 | ABCB11 (0.40) | ALDH1A1L3MBTL1TDP1ATMABCB11 | |
| SCHEMBL9643350 | 0.83 | UCHL1 (0.41) | ALDH1A1L3MBTL1ABCB11SMN1; SMN2UCHL1 | |
| SCHEMBL9641799 | 0.82 | ABCB11 (0.41) | ALDH1A1L3MBTL1ABCB11MEN1KMT2A | |
| SCHEMBL9642952 | 0.82 | ABCB11 (0.53) | ALDH1A1L3MBTL1ABCB11SMN1; SMN2UCHL1 | |
| SCHEMBL9643164 | 0.82 | ABCB11 (0.62) | ALDH1A1L3MBTL1TDP1ATMABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |