Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644519 | 0.83 | KMT2A (0.44) | PTGES2ALDH1A1MCOLN3KEAP1NFE2L2 | |
| SCHEMBL9644754 | 0.79 | HSD11B1 (0.54) | ALDH1A1TP53POLBHTTKMT2A | |
| SCHEMBL9644500 | 0.75 | GAA (0.47) | ALDH1A1POLBDDR1HSD11B1 | |
| SCHEMBL17783669 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MCOLN3POLBKEAP1NFE2L2 | |
| SCHEMBL9643700 | 0.74 | MAOA (0.41) | PTGES2ALDH1A1SMN1; SMN2ALOX12CA1 | |
| SCHEMBL9645793 | 0.71 | PTGES2 (0.44) | PTGES2ALDH1A1HTTKMT2AHSD11B1 | |
| SCHEMBL9644833 | 0.71 | KMT2A (0.46) | ALDH1A1KMT2AMEN1HSD11B1 | |
| SCHEMBL581476 | 0.70 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2POLBKEAP1NFE2L2 | |
| SCHEMBL2068996 | 0.70 | FFAR1 (0.51) | ALDH1A1POLBKEAP1NFE2L2ALOX12 | |
| SCHEMBL9721164 | 0.70 | ITGA1 (0.48) | PTGES2KMT2AMEN1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5123953-A | DIHALOGENATED HERBICIDAL SULPHONES | RHONE-POULENC AGROCHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |