Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 5/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646475 | 0.94 | DRD3 (0.53) | DRD3HTR1AADRA1ADRD1SLC6A4 | |
| SCHEMBL9646450 | 0.91 | KDM4E (0.49) | DRD3HTR1AADRA1AABCB11ADRA2A | |
| SCHEMBL9210834 | 0.84 | DRD3 (0.58) | DRD3HTR1AADRA1AABCB11ADRA2A | |
| SCHEMBL9646137 | 0.84 | HTR1A (0.60) | HTR1AHTR7KDM4E | |
| SCHEMBL9646526 | 0.84 | NOTUM (0.44) | HTR1ADRD1DRD2HTR7HTR2A | |
| SCHEMBL9645712 | 0.82 | BRAF (0.46) | DRD3HTR1AADRA1ADRD2HTR7 | |
| SCHEMBL9647583 | 0.81 | KDM4E (0.58) | HTR1ASLC6A4HTR7HTR2AMAPT | |
| SCHEMBL9644860 | 0.80 | KDM4E (0.49) | HTR1AHTR7KDM4E | |
| SCHEMBL9644779 | 0.79 | HTR1A (0.48) | HTR1AHTR7KDM4E | |
| SCHEMBL9646338 | 0.79 | DRD2 (0.52) | DRD3HTR1ADRD1DRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | claimed |
| US-5084456-A | Analgesics | SCIENCE ET ORGANISATION (FR) | 1992-01-28 | — | — | US | disclosed |