Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 5/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644841 | 0.84 | DRD3 (0.53) | DRD3HTR1AADRA1AABCB11ADRA2A | |
| SCHEMBL9215528 | 0.84 | HTR7 (0.59) | HTR1AKCNH2HTR7 | |
| SCHEMBL9216657 | 0.81 | MEN1 (0.50) | HTR1ASLC6A4HTR7HTR2AMAPT | |
| SCHEMBL9646475 | 0.79 | DRD3 (0.53) | DRD3HTR1AADRA1ADRD1SLC6A4 | |
| SCHEMBL9219564 | 0.78 | HTR1A (0.69) | HTR1AHTR7 | |
| SCHEMBL9219074 | 0.78 | HTR1A (0.66) | DRD3HTR1AHTR7 | |
| SCHEMBL9646450 | 0.77 | KDM4E (0.49) | DRD3HTR1AADRA1AABCB11ADRA2A | |
| SCHEMBL9219866 | 0.77 | TMEM97 (0.49) | DRD2SIGMAR1 | |
| SCHEMBL9221444 | 0.76 | SIGMAR1 (0.49) | SIGMAR1KDM4EPOLB | |
| SCHEMBL9597086 | 0.76 | TMEM97 (0.51) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487408-B1 | Oxazolopyridine derivatives, process for their preparation and pharmaceutical compositions comprising the same | ADIR (FR) | 1995-06-21 | — | — | EP | claimed |
| US-5130311-A | Analgesics or antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1992-07-14 | — | — | US | claimed |
| US-5242923-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-09-07 | — | — | US | disclosed |
| US-5130311-A | Analgesics or antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1992-07-14 | — | — | US | disclosed |